Red yeast rice has become the most-popular and, for many, the most effective over-the-counter option for cholesterol support. Red yeast rice is the active ingredient in Cholestene. In fact Cholestene is a pretty typical red yeast rice supplement, with 600 mg per capsule like many other brands. It may or may not be the best value on a dollars-per-milligram basis compared to other brands, but Cholestene is one of the most popular red yeast rice products, so it's definitely working for some people. Users will need blood tests to determine what effect Cholestene is having on cholesterol levels, and with a series of tests over the course of a few months, determine the lowest effective dose of Cholestene.