If you're using high potency alpha lipoic acid for liver detox or blood sugar support, there's a few things you should know. One is that the long term use of high potency ALA can undermine your biotin status. Biotin is a B vitamin that also supports blood sugar balance, as well as hair skin and nail health. Another factor is that high potency alpha lipoic acid absorbs very quickly making divided smaller doses theoretically a better way to take ALA, but much less practical in real-life terms. Jarrow Alpha Lipoic Sustain 300 solves both problems by using a time-release high-potency 300 mg capsule and by including a sensible amount of biotin.