Oligomeric Procyandins are the powerful antioxidant nutrients found in grape seed and grape skin extracts. Although antioxidants benefit overall health, OPC's like those in Nature's Way TRU-OPC's are usually recommended for support of blood vessels and cardiovascular health. Vascular tissue is highly susceptible to oxidative damage, which sets several harmful processes in motion. So one of the best ways to protect your vascular health is to use potent antioxidants like TRU-OPC from Nature's Way. Experts like Dr. Perricone also recommend grape seed extract antioxidants for skin heath too.